Medical network - on March 21, cancer is the second largest disease of the world's death, the world health organization (WHO) published by the world cancer report 2014, "said global deaths from cancer patients and increase are disturbingly, nearly half of new cancer cases in Asia, mostly in China. Cancer cases worldwide, the report also predicts will present rapid growth trend, is increasing year by year from 2012 in 14 million to 2012 in 19 million, by 2035 will reach 2035 people, of which China will account for 21.9% of the global total.
Two-time Nobel laureate Linus Pauling once said: "everyone should know the fight against cancer is basically a lie. I'm afraid there is nothing more frightening than hear cancer." Indeed, this is known as the century of the cancer disease, like a head of a disaster, lurking in our life.
Chemotherapy is the important method to cure malignant tumor, widely used in clinic, but its adverse reactions, patients often experience symptoms such as nausea, vomiting, lower the quality of life. Research has shown that chemotherapy drugs can stimulate the release of 5 - HT in the body, and through 5 - HT3 receptor mediated would transmit the signals to vomiting center leading to vomiting.
Cause vomiting drugs cisplatin, cyclophosphamide, high-dose methotrexate, mitomycin, carboplatin, ifosfamide, etc. Especially with the highest incidence of cisplatin to vomit, degree of vomiting caused by the most serious, often the first element of chemotherapy for patients refused again. Acute nausea and vomiting caused by chemotherapy, can be divided into delayed vomiting. 1 ~ 6 hours after acute vomiting develops in drug use, particularly in not received chemotherapy, but there are exceptions. When high dose cyclophosphamide intravenous medication, vomiting in 9 ~ l8 hours after medication. Vomiting caused by cisplatin in 6 ~ 8 hours after medication. Delayed vomiting means occurred in 17 ~ 24 hours after the chemotherapy of vomiting.
Frequent nausea and vomiting state change will cause the patient's comfort, the appetite of serious loss, many patients even malnutrition, severe cases can produce fear, make the immune system of their fragile hit again, thus affecting the smooth progress of chemotherapy. Therefore, 5 HT3 receptor antagonist for chemotherapy to vomit inhibition, clinically significant.
Hydrochloric acid tropane SiQiong is listed after the Dan SiQiong and gamla SiQiong third 5 - HT3 receptor antagonist, developed by the Swiss Sandoz company, listed in the Netherlands for the first time in 1992. At present is mainly used for clinical prevention and treatment of nausea and vomiting caused by chemotherapy of cancers. Tropane SiQiong compared with those of other 5 - HT3 receptor antagonists have low light, good tolerance and side effects between drug reactions and effect for a long time. Single dose delivery, no tolerance, in each chemotherapy regimen can be repeated use. No extrapyramidal effects. The recommended dose, 5 mg each time, once per day, can be safely used in adults, the elderly, patients with hepatic or renal dysfunction and children 2 years of age or older.
Hydrochloric acid tropane SiQiong piece as 2017 new oral anti-nausea drugs, the new medical insurance directory has the following advantages:
First, adherence: long half-life, served only once a day. No adjustment of dosage is needed for liver and kidney function is not complete;
Second, effectiveness: a potent anti-nausea effect, the medium inside the double block gag reflex chemical transfer, and clinical use is widespread, not only for vomiting caused by cancer, radiation therapy, also used for anesthesia, postoperative nausea and vomiting;
Third, security: mild adverse reactions.
Experiments show that the hydrochloric acid tropane SiQiong can effectively prevent chemotherapy induced nausea and vomiting, curative effect is better than Dan SiQiong. And hydrochloric acid tropane SiQiong generally well tolerated, under the recommended dose of adverse reactions to one sex.
The exclusive rights to produce varieties - neither Ann ® hydrochloride tropane SiQiong slices
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